Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding.
A causative role for single nucleotide polymorphisms (SNPs) in many genetic disorders has become evident through numerous genome-wide association studies. However, identification of these common causal variants and the molecular mechanisms underlying these associations remains a major challenge. Dif...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-09-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3459973?pdf=render |