Virtual screening for potential inhibitors of Mcl-1 conformations sampled by normal modes, molecular dynamics, and nuclear magnetic resonance

Virtual screening for potential inhibitors of Mcl-1 conformations sampled by normal modes, molecular dynamics, and nuclear magnetic resonance

Yitav Glantz-Gashai,* Tomer Meirson,* Eli Reuveni, Abraham O Samson Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel *These authors contributed equally to this work Abstract: Myeloid cell leukemia-1 (Mcl-1) is often overexpressed in human cancer and is an important target fo...

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Bibliographic Details
Main Authors: Glantz-Gashai Y, Meirson T, Reuveni E, Samson AO
Format: Article
Language:English
Published: Dove Medical Press 2017-06-01
Series:Drug Design, Development and Therapy
Subjects:
Virtual screening
MCL-1
Molecular Dynamics
NMR
Normal modes
Online Access:https://www.dovepress.com/virtual-screening-for-potential-inhibitors-of-mcl-1-conformations-samp-peer-reviewed-article-DDDT

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https://www.dovepress.com/virtual-screening-for-potential-inhibitors-of-mcl-1-conformations-samp-peer-reviewed-article-DDDT

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