Effect of polymorphism in Rhinolophus affinis ACE2 on entry of SARS-CoV-2 related bat coronaviruses.

Effect of polymorphism in Rhinolophus affinis ACE2 on entry of SARS-CoV-2 related bat coronaviruses.

Bat coronavirus RaTG13 shares about 96.2% nucleotide sequence identity with that of SARS-CoV-2 and uses human and Rhinolophus affinis (Ra) angiotensin-converting enzyme 2 (ACE2) as entry receptors. Whether there are bat species other than R. affinis susceptible to RaTG13 infection remains elusive. H...

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Bibliographic Details
Main Authors: Pei Li, Jiaxin Hu, Yan Liu, Xiuyuan Ou, Zhixia Mu, Xing Lu, Fuwen Zan, Mengmeng Cao, Lin Tan, Siwen Dong, Yao Zhou, Jian Lu, Qi Jin, Jianwei Wang, Zhiqiang Wu, Yingtao Zhang, Zhaohui Qian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011116

Internet

https://doi.org/10.1371/journal.ppat.1011116

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