ARRB1 Regulates Metabolic Reprogramming to Promote Glycolysis in Stem Cell-Like Bladder Cancer Cells

β-arrestin 1 (ARRB1) is a scaffold protein that regulates signaling downstream of G protein-coupled receptors (GPCRs). In the current work, we investigated the role of ARRB1 in regulating the metabolic preference of cancer stem cell (CSC)-like cells in bladder cancer (BC). We show that ARRB1 is cruc...

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Bibliographic Details
Main Authors: Kenza Mamouni, Jeongheun Kim, Bal L. Lokeshwar, Georgios Kallifatidis
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/8/1809