HOXA-AS2 enhances GBM cell malignancy by suppressing miR-2116-3p thereby upregulating SERPINA3

Abstract Background Glioblastoma (GBM) is malignant, demanding more attention to the improvement of the diagnosis and therapy. LncRNAs have been implicated in the malignancy of GBM cells. Methods HOXA-AS2, miR-2116-3p and SERPINA3 expression levels in GBM tissues and cell lines were detected by qRT-...

Full description

Bibliographic Details
Main Authors: Jianrui Sun, Lin Wang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09462-y