INFLUENCE OF DEXAMETHASONE-MODIFIED DENDRITIC CELLS GENERATED WITH IFNα UPON AUTOLOGOUS T LYMPHOCYTE FUNCTIONS IN THE PATIENTS WITH RHEUMATOID ARTHRITIS

INFLUENCE OF DEXAMETHASONE-MODIFIED DENDRITIC CELLS GENERATED WITH IFNα UPON AUTOLOGOUS T LYMPHOCYTE FUNCTIONS IN THE PATIENTS WITH RHEUMATOID ARTHRITIS

Dendritic cells (DCs) play a key role in maintaining the peripheral tolerance of lymphocytes to autoantigens. Recovery of immunological tolerance in autoimmune diseases, particularly, in rheumatoid arthritis (RA) is considered a new therapeutic strategy. The aim of this work was to study the effect...

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Bibliographic Details
Main Authors: Yu. D. Kurochkina, T. V. Tyrinova, O. Yu. Leplina, M. A. Tikhonova, A. E. Sizikov, A. E. Sulutian, O. A. Chumasova, A. A. Ostanin, E. R. Chernykh
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2019-12-01
Series:Медицинская иммунология
Subjects:
dendritic cells
interferon-α
dexamethasone
auto-mlc
apoptosis
anergy
cytokines
tr1
rheumatoid arthritis
Online Access:https://www.mimmun.ru/mimmun/article/view/1622

Internet

https://www.mimmun.ru/mimmun/article/view/1622

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