TXNIP: A key protein in the cellular stress response pathway and a potential therapeutic target

Abstract Thioredoxin-interacting protein (TXNIP), which is also known as thioredoxin-binding protein 2 (TBP2), directly interacts with the major antioxidant protein thioredoxin (TRX) and inhibits its antioxidant function and expression. However, recent studies have demonstrated that TXNIP is a multi...

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Bibliographic Details
Main Authors: Eui-Hwan Choi, Sun-Ji Park
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01019-8