Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus

Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus

Abstract Background Lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus erythematosus patients. Mesangial cells (MCs) comprise a third of the glomerular cells and are key contributors to fibrotic changes within the kidney. This project aims to identify the roles of MCs in an in v...

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Bibliographic Details
Main Authors: Rachael D. Wright, Paraskevi Dimou, Sarah J. Northey, Michael W. Beresford
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Inflammation
Subjects:
Lupus nephritis
Mesangial cells
Fibrosis
Online Access:http://link.springer.com/article/10.1186/s12950-019-0227-x

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http://link.springer.com/article/10.1186/s12950-019-0227-x

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