RSK1 and RSK2 serine/threonine kinases regulate different transcription programs in cancer

RSK1 and RSK2 serine/threonine kinases regulate different transcription programs in cancer

The 90 kDa ribosomal S6 kinases (RSKs) are serine threonine kinases comprising four isoforms. The isoforms can have overlapping functions in regulation of migration, invasion, proliferation, survival, and transcription in various cancer types. However, isoform specific differences in RSK1 versus RSK...

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Bibliographic Details
Main Authors: Won Seok Yang, Maisel J. Caliva, Vedbar S. Khadka, Maarit Tiirikainen, Michelle L. Matter, Youping Deng, Joe W. Ramos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RSK
transcription
microarray
cell cycle
immune response
kinase
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1015665/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1015665/full

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