Effect of Compaction Pressure on the Enzymatic Activity of Pancreatin in Directly Compressible Formulations

Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated. In the present study, pancreatin was employed as a model enzyme mixture, which was formulated in tablet f...

Full description

Bibliographic Details
Main Authors: Daniel Zakowiecki, Peter Edinger, Tobias Hess, Jadwiga Paszkowska, Marcela Staniszewska, Svitlana Romanova, Grzegorz Garbacz
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/9/2224