Immunomodulation Induced During Interferon-α Therapy Impairs the Anti-HBV Immune Response Through CD24+CD38hi B Cells
Type I interferon is widely used for antiviral therapy, yet has yielded disappointing results toward chronic HBV infection. Here we identify that PEG-IFNα-2b therapy toward persistent infection in humans is a double-edged sword of both immunostimulation and immunomodulation. Our studies of this rand...
| Main Authors: | , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Frontiers Media S.A.
2020-12-01
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| 丛编: | Frontiers in Immunology |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.591269/full |