Mouse microglia express unique miRNA-mRNA networks to facilitate age-specific functions in the developing central nervous system

Abstract Microglia regulate multiple processes in the central nervous system, exhibiting a considerable level of cellular plasticity which is facilitated by an equally dynamic transcriptional environment. While many gene networks that regulate microglial functions have been characterised, the influe...

Full description

Bibliographic Details
Main Authors: Alexander D. Walsh, Sarrabeth Stone, Saskia Freytag, Andrea Aprico, Trevor J. Kilpatrick, Brendan R. E. Ansell, Michele D. Binder
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04926-8