Bile Acid Dysregulation Is Intrinsically Related to Cachexia in Tumor-Bearing Mice

Bile Acid Dysregulation Is Intrinsically Related to Cachexia in Tumor-Bearing Mice

Bile acids exert diverse actions on host metabolism and immunity through bile acid-activated receptors, including Takeda G protein-coupled receptor 5 (TGR5). We have recently evidenced an alteration in bile acids in cancer cachexia, an inflammatory and metabolic syndrome contributing to cancer death...

Full description

Bibliographic Details
Main Authors: Morgane M. Thibaut, Justine Gillard, Adeline Dolly, Martin Roumain, Isabelle A. Leclercq, Nathalie M. Delzenne, Giulio G. Muccioli, Laure B. Bindels
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
ursodeoxycholic acid
bile flow
non-cachectic C26 mice
NC26
G protein-coupled bile acid receptor
GPBAR1
Online Access:https://www.mdpi.com/2072-6694/13/24/6389

Internet

https://www.mdpi.com/2072-6694/13/24/6389

Similar Items