Amide proton transfer MRI differentiates between progressive multifocal leukoencephalopathy and malignant brain tumors: a pilot study

Abstract Background Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nerve system caused by the John Cunningham virus. On MRI, PML may sometimes appear similar to primary central nervous system lymphoma (PCNSL) and glioblastoma multiforme (GBM). The purpose...

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Bibliographic Details
Main Authors: Hirofumi Koike, Minoru Morikawa, Hideki Ishimaru, Reiko Ideguchi, Masataka Uetani, Takeshi Hiu, Takayuki Matsuo, Mitsuharu Miyoshi
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Medical Imaging
Subjects:
Online Access:https://doi.org/10.1186/s12880-022-00959-3