Growth‐mediated negative feedback shapes quantitative antibiotic response

Growth‐mediated negative feedback shapes quantitative antibiotic response

Abstract Dose–response relationships are a general concept for quantitatively describing biological systems across multiple scales, from the molecular to the whole‐cell level. A clinically relevant example is the bacterial growth response to antibiotics, which is routinely characterized by dose–resp...

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Bibliographic Details
Main Authors: S Andreas Angermayr, Tin Yau Pang, Guillaume Chevereau, Karin Mitosch, Martin J Lercher, Tobias Bollenbach
Format: Article
Language:English
Published: Springer Nature 2022-09-01
Series:Molecular Systems Biology
Subjects:
antibiotics
dihydrofolate reductase (DHFR)
dose–response curve
feedback loops
resource allocation model
Online Access:https://doi.org/10.15252/msb.202110490

Internet

https://doi.org/10.15252/msb.202110490

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