E3 Ubiquitin Ligases as Cancer Targets and Biomarkers

E3 ubiquitin ligases are a large family of proteins that are engaged in the regulation of the turnover and activity of many target proteins. Together with ubiquitinactivating enzyme El and ubiquitin-conjugating enzyme E2, E3 ubiquitin ligases catalyze the ubiquitination of a variety of biologically...

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Bibliographic Details
Main Author: Yi Sun
Format: Article
Language:English
Published: Elsevier 2006-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800035