Coumarin-Based Compounds as Inhibitors of Tyrosinase/Tyrosine Hydroxylase: Synthesis, Kinetic Studies, and In Silico Approaches

Coumarin-Based Compounds as Inhibitors of Tyrosinase/Tyrosine Hydroxylase: Synthesis, Kinetic Studies, and In Silico Approaches

Cancer represents the main cause of morbidity and mortality worldwide, constituting a serious health problem. In this context, melanoma represents the most aggressive and fatal type of skin cancer, with death rates increasing every year. Scientific efforts have been addressed to the development of i...

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Bibliographic Details
Main Authors: Jéssica Alves Nunes, Rodrigo Santos Aquino de Araújo, Fabrícia Nunes da Silva, Joanna Cytarska, Krzysztof Z. Łączkowski, Sílvia Helena Cardoso, Francisco Jaime Bezerra Mendonça-Júnior, Edeildo Ferreira da Silva-Júnior
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
tyrosinase
melanoma
skin cancer
copper
inhibitors
dynamics
Online Access:https://www.mdpi.com/1422-0067/24/6/5216

Internet

https://www.mdpi.com/1422-0067/24/6/5216

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