Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time

Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time

Epigenome-wide association studies (EWAS) have focused primarily on DNA methylation as a chemically stable and functional epigenetic modification. However, the stability and accuracy of the measurement of methylation in different tissues and extraction types is still being actively studied, and the...

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Bibliographic Details
Main Authors: Marie Forest, Kieran J. O'Donnell, Greg Voisin, Helene Gaudreau, Julia L. MacIsaac, Lisa M. McEwen, Patricia P. Silveira, Meir Steiner, Michael S. Kobor, Michael J. Meaney, Celia M.T. Greenwood
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Epigenetics
Subjects:
intraclass correlations
methylation
redundancy analysis
replication
tissue stability
Online Access:http://dx.doi.org/10.1080/15592294.2017.1411443

Internet

http://dx.doi.org/10.1080/15592294.2017.1411443

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