Analysing the meta-interaction between pathways by gene set topological impact analysis

Abstract Background Pathway analysis is widely applied in transcriptome analysis. Given certain transcriptomic changes, current pathway analysis tools tend to search for the most impacted pathways, which provides insight into underlying biological mechanisms. Further refining of the enriched pathway...

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Bibliographic Details
Main Authors: Shen Yan, Xu Chi, Xiao Chang, Mengliang Tian
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-07148-y