DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice

DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice

The manchette is a transient and unique structure present in elongating spermatids and required for proper differentiation of the germ cells during spermatogenesis. Previous work indicated that the MEIG1/PACRG complex locates in the manchette and is involved in the transport of cargos, such as SPAG1...

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Bibliographic Details
Main Authors: Yi Tian Yap, Wei Li, Qian Huang, Qi Zhou, David Zhang, Yi Sheng, Ljljiana Mladenovic-Lucas, Siu-Pok Yee, Kyle E Orwig, James G Granneman, David C Williams Jr, Rex A Hess, Aminata Toure, Zhibing Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-04-01
Series:eLife
Subjects:
DNALI1
manchette
cargo transport
spermatogenesis
Online Access:https://elifesciences.org/articles/79620

Internet

https://elifesciences.org/articles/79620

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