Simplified Iohexol-Based Method for Measurement of Glomerular Filtration Rate in Goats and Pigs

The preclinical evaluation of novel therapies for chronic kidney disease requires a simple method for the assessment of kidney function in a uremic large animal model. An intravenous bolus of iohexol was administered to goats (13 measurements in <i>n</i> = 3 goats) and pigs (23 measureme...

Full description

Bibliographic Details
Main Authors: Maaike K. van Gelder, Jasper Stevens, Tobias T. Pieters, Koen R. D. Vaessen, Jaap A. Joles, Marianne C. Verhaar, Karin G. F. Gerritsen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/6/461