Detectable Lipidomes and Metabolomes by Different Plasma Exosome Isolation Methods in Healthy Controls and Patients with Advanced Prostate and Lung Cancer

Detectable Lipidomes and Metabolomes by Different Plasma Exosome Isolation Methods in Healthy Controls and Patients with Advanced Prostate and Lung Cancer

Circulating exosomes in the blood are promising tools for biomarker discovery in cancer. Due to their heterogeneity, different isolation methods may enrich distinct exosome cargos generating different omic profiles. In this study, we evaluated the effects of plasma exosome isolation methods on detec...

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Bibliographic Details
Main Authors: Alex C. Soupir, Yijun Tian, Paul A. Stewart, Yury O. Nunez-Lopez, Brandon J. Manley, Bruna Pellini, Amanda M. Bloomer, Jingsong Zhang, Qianxing Mo, Douglas C. Marchion, Min Liu, John M. Koomen, Erin M. Siegel, Liang Wang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
exosome extraction
cancer multiome
plasma omics
circulating lipids
circulating metabolites
Online Access:https://www.mdpi.com/1422-0067/24/3/1830

Internet

https://www.mdpi.com/1422-0067/24/3/1830

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