Characterization of cross-tissue genetic-epigenetic effects and their patterns in schizophrenia

Characterization of cross-tissue genetic-epigenetic effects and their patterns in schizophrenia

Abstract Background One of the major challenges in current psychiatric epigenetic studies is the tissue specificity of epigenetic changes since access to brain samples is limited. Peripheral tissues have been studied as surrogates but the knowledge of cross-tissue genetic-epigenetic characteristics...

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Bibliographic Details
Main Authors: Dongdong Lin, Jiayu Chen, Nora Perrone-Bizzozero, Juan R. Bustillo, Yuhui Du, Vince D. Calhoun, Jingyu Liu
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Genome Medicine
Subjects:
Genetic
DNA methylation
meQTLs
eQTL
Cross-tissue
Schizophrenia
Online Access:http://link.springer.com/article/10.1186/s13073-018-0519-4

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http://link.springer.com/article/10.1186/s13073-018-0519-4

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