Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt

Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt

Abstract Background Glucose fluctuations may be involved in the pathophysiological process of cardiomyocyte apoptosis, but the exact mechanism remains elusive. This study focused on exploring the mechanisms related to glucose fluctuation-induced cardiomyocyte apoptosis. Methods Diabetic rats establi...

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Bibliographic Details
Main Authors: Zhen-Ye Zhang, Lu Pan, Shipeng Dang, Ning Wang, Shan-Ying Zhao, Feng Li, Li-Da Wu, Lei Zhang, Huan-Huan Liu, Ning Zhao, Ya-Juan Yang, Ling-Ling Qian, Tong Liu, Ru-Xing Wang
Format: Article
Language:English
Published: BMC 2024-09-01
Series:BMC Cardiovascular Disorders
Subjects:
Glucose fluctuation
Cardiomyocyte apoptosis
Thioredoxin-interacting protein
Protein kinase B/Akt
Online Access:https://doi.org/10.1186/s12872-024-04134-0

Internet

https://doi.org/10.1186/s12872-024-04134-0

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