Genetic architecture of intrinsic antibiotic susceptibility.

BACKGROUND:Antibiotic exposure rapidly selects for more resistant bacterial strains, and both a drug's chemical structure and a bacterium's cellular network affect the types of mutations acquired. METHODOLOGY/PRINCIPAL FINDINGS:To better characterize the genetic determinants of antibiotic...

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Bibliographic Details
Main Authors: Hany S Girgis, Alison K Hottes, Saeed Tavazoie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2680486?pdf=render