The past, present and future of immune repertoire biology – the rise of next-generation repertoire analysis

The past, present and future of immune repertoire biology – the rise of next-generation repertoire analysis

T and B cell repertoires are collections of lymphocytes, each characterised by its antigen-specific receptor. We review here classical technologies and analysis strategies developed to assess Immunoglobulin (IG) and T cell receptor (TR) repertoire diversity, and describe recent advances in the field...

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Bibliographic Details
Main Authors: Adrien eSix, Encarnita eMariotti-Ferrandiz, Wahiba eChaara, Susana eMagadan, Hang-Phuong ePham, Marie-Paule eLefranc, Thierry eMora, Véronique eThomas-Vaslin, Aleksandra M. Walczak, Pierre eBoudinot
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
B cell repertoire
modelling
Next-generation sequencing
statistics
immune receptors
gene nomenclature
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00413/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00413/full

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