The past, present and future of immune repertoire biology – the rise of next-generation repertoire analysis

The past, present and future of immune repertoire biology – the rise of next-generation repertoire analysis

T and B cell repertoires are collections of lymphocytes, each characterised by its antigen-specific receptor. We review here classical technologies and analysis strategies developed to assess Immunoglobulin (IG) and T cell receptor (TR) repertoire diversity, and describe recent advances in the field...

Full description

Bibliographic Details
Main Authors:	Adrien eSix, Encarnita eMariotti-Ferrandiz, Wahiba eChaara, Susana eMagadan, Hang-Phuong ePham, Marie-Paule eLefranc, Thierry eMora, Véronique eThomas-Vaslin, Aleksandra M. Walczak, Pierre eBoudinot
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-11-01
Series:	Frontiers in Immunology
Subjects:	B cell repertoire modelling Next-generation sequencing statistics immune receptors gene nomenclature
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00413/full

Similar Items

RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy
by: Wahiba Chaara, et al.
Published: (2018-05-01)

Dynamical and mechanistic reconstructive approaches of T lymphocyte dynamics :Using visual modelling languages to bridge the gap between immunologists, theoreticians and programmers
by: Véronique eTHOMAS-VASLIN, et al.
Published: (2013-10-01)

The astonishing diversity of Ig classes and B cell repertoires in teleost fish
by: Simon eFillatreau, et al.
Published: (2013-02-01)

T follicular helper and T follicular regulatory cells have different TCR specificity
by: Ana Raquel Maceiras, et al.
Published: (2017-04-01)

A complex immunological idiotypic network for maintenance of tolerance
by: Véronique eTHOMAS-VASLIN, et al.
Published: (2014-07-01)

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria.
by: Encarnita Mariotti-Ferrandiz, et al.
Published: (2016-01-01)

Decadal region-wide and glacier-wide mass balances derived from multi-temporal ASTER satellite digital elevation models. Validation over the Mont-Blanc area
by: Etienne eBerthier, et al.
Published: (2016-06-01)

GeVaDSs – decision support system for novel Genetic Vaccine development process
by: Blazewicz Jacek, et al.
Published: (2012-05-01)

State-transition diagrams for biologists.
by: Hugues Bersini, et al.
Published: (2012-01-01)

Endogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection.
by: Caroline Montaudouin, et al.
Published: (2010-01-01)

What’s really wrong with cognitive behavioural therapy for psychosis?
by: Neil eThomas, et al.
Published: (2015-03-01)

Active regulatory T-cells contribute to broadened T-cell repertoire diversity in ivIg-treated SLE patients
by: Costa Nuno, et al.
Published: (2011-11-01)

Regulatory T Cells As Supporters of Psychoimmune Resilience: Toward Immunotherapy of Major Depressive Disorder
by: Pierre Ellul, et al.
Published: (2018-03-01)

Human thymopoiesis produces polyspecific CD8+ α/β T cells responding to multiple viral antigens
by: Valentin Quiniou, et al.
Published: (2023-03-01)

A comprehensive analysis of the microbial communities of healthy and diseased marine macroalgae and the detection of known and potential bacterial pathogens
by: Torsten eThomas
Published: (2015-02-01)

Bundling Actin Filaments From Membranes: Some Novel Players
by: Clément eThomas
Published: (2012-08-01)

Prochlorococcus and Synechococcus have evolved different adaptive mechanisms to cope with light and UV stress
by: Daniella eMella-Flores, et al.
Published: (2012-08-01)

Editorial for: Microbial symbiosis of marine sessile hosts- diversity and function
by: Suhelen eEgan, et al.
Published: (2015-06-01)

Short-term rhizosphere effect on available carbon sources, phenanthrene degradation and active microbiome in an aged-contaminated industrial soil
by: François eThomas, et al.
Published: (2016-02-01)

Root-associated bacterial endophytes from Ralstonia solanacearum resistant and susceptible tomato cultivars and their pathogen antagonistic effects
by: Reshmi eUpreti, et al.
Published: (2015-04-01)

Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling
by: Johannes Trück, et al.
Published: (2021-05-01)

Dynamic perturbations of the T-cell receptor repertoire in chronic HIV infection and following antiretroviral therapy.
by: James Malcolm Heather, et al.
Published: (2016-01-01)

Regulatory T lymphocytes/Th17 lymphocytes imbalance in autism spectrum disorders: evidence from a meta-analysis
by: Pierre Ellul, et al.
Published: (2021-10-01)

How neuroscience and behavioral genetics improve psychiatric assessment: Report on a violent murder case
by: Davide Rigoni, et al.
Published: (2010-10-01)

Use of machine learning in osteoarthritis research: a systematic literature review
by: Francis Berenbaum, et al.
Published: (2022-03-01)

The effects of physical activity on brain structure
by: Adam eThomas, et al.
Published: (2012-03-01)

Novel biologic therapies for thymic epithelial tumors
by: YUANBIN eCHEN, et al.
Published: (2014-05-01)

Low and then high frequency oscillations of distinct right cortical networks are progressively enhanced by medium and long term Satyananda Yoga meditation practice
by: John eThomas, et al.
Published: (2014-06-01)

Effects due to rhizospheric soil application of an antagonistic bacterial endophyte on native bacterial community and its survival in soil: A case study with Pseudomonas aeruginosa from banana
by: Pious eThomas, et al.
Published: (2016-04-01)

A methodological review of meditation research
by: Marc Maurice Cohen, et al.
Published: (2014-07-01)

Restoration of tryptophan hydroxylase functions and serotonin content in the Atlantic croaker hypothalamus by antioxidant treatment during hypoxic stress
by: Md. Saydur Rahman, et al.
Published: (2014-05-01)

A dynamic interplay between membranes and the cytoskeleton critical for cell development and signaling
by: Clément eThomas, et al.
Published: (2014-07-01)

Pan-arctic trends in terrestrial dissolved organic matter from optical measurements
by: Paul James Mann, et al.
Published: (2016-03-01)

Electrophysiological cross-language neighborhood density effects in late and early English-Welsh bilinguals
by: Giordana eGrossi, et al.
Published: (2012-10-01)

Neural dynamics of reward probability coding: a Magnetoencephalographic study in humans
by: Julie eThomas, et al.
Published: (2013-11-01)

Low spatial frequency bias in schizophrenia is not face specific: When the integration of coarse and fine information fails
by: Vincent eLaprevote, et al.
Published: (2013-05-01)

Perceived Mathematical Ability under Challenge: A Longitudinal Perspective on Sex Segregation among STEM Degree Fields
by: Samantha eNix, et al.
Published: (2015-06-01)

An ultrahigh field Magnetic Resonance Spectroscopy study of post exercise brain lactate, glutamate and glutamine change in the human brain.
by: Andrea eDennis, et al.
Published: (2015-12-01)

Monstres hétérodymes : cause rare de dystocie au cours d´un accouchement
by: Jihad Jamor, et al.
Published: (2020-04-01)

Modelling T cell proliferation: Dynamics heterogeneity depending on cell differentiation, age, and genetic background.
by: Julien Vibert, et al.
Published: (2017-03-01)