Nuclear localization of TET2 requires β-catenin activation and correlates with favourable prognosis in colorectal cancer

Nuclear localization of TET2 requires β-catenin activation and correlates with favourable prognosis in colorectal cancer

Abstract Mutation-induced malfunction of ten-eleven translocation methylcytosine dioxygenase 2 (TET2) is widely reported in haematological malignancies. However, the role of TET2 in solid cancers, including colorectal cancer (CRC), is unclear. Here, we found that TET2 malfunction in CRC is mostly du...

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Bibliographic Details
Main Authors: Changpeng Li, Jingcai He, Fei Meng, Fuhui Wang, Hao Sun, Huizhong Zhang, Linna Dong, Mengdan Zhang, Qiaoran Xu, Lining Liang, Yuan Li, Tingting Yang, Meiai He, Tao Wang, Jiechun Lin, Jiaqi Sun, Qiuling Huang, Lin Guo, Xiaofei Zhang, Shijuan Mai, Hui Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06038-x

Internet

https://doi.org/10.1038/s41419-023-06038-x

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