Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury.

Interruption of blood supply to the heart is a leading cause of death and disability. However, the molecular events that occur during heart ischemia, and how these changes prime consequent cell death upon reperfusion, are poorly understood. Protein SUMOylation is a post-translational modification th...

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Bibliographic Details
Main Authors: Nadiia Rawlings, Laura Lee, Yasuko Nakamura, Kevin A Wilkinson, Jeremy M Henley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213331