The Root Extract of <i>Peucedanum praeruptorum</i> Dunn Exerts Anticancer Effects in Human Non-Small-Cell Lung Cancer Cells with Different <i>EGFR</i> Mutation Statuses by Suppressing MET Activity

The Root Extract of <i>Peucedanum praeruptorum</i> Dunn Exerts Anticancer Effects in Human Non-Small-Cell Lung Cancer Cells with Different <i>EGFR</i> Mutation Statuses by Suppressing MET Activity

The aim of this study was to investigate the anticancer effects of the root extract of <i>Peucedanum praeruptorum</i> Dunn (EPP) in human non-small-cell lung cancer (NSCLC) cells and explore the mechanisms of action. We used four types of human lung cancer cell lines, including H1299 (&l...

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Bibliographic Details
Main Authors: Hyun-Ji Park, Jae-Hoon Jeong, Shin-Hyung Park
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
<i>Peucedanum praeruptorum</i> Dunn
non-small-cell lung cancer
<i>EGFR</i> mutation
EGFR TKI resistance
apoptosis
MET
Online Access:https://www.mdpi.com/1420-3049/27/7/2360

Internet

https://www.mdpi.com/1420-3049/27/7/2360

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