Ex vivo expansion potential of murine hematopoietic stem cells is a rare property only partially predicted by phenotype

The scarcity of hematopoietic stem cells (HSCs) restricts their use in both clinical settings and experimental research. Here, we examined a recently developed method for expanding rigorously purified murine HSCs ex vivo. After 3 weeks of culture, only 0.1% of cells exhibited the input HSC phenotype...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Qinyu Zhang, Rasmus Olofzon, Anna Konturek-Ciesla, Ouyang Yuan, David Bryder
स्वरूप: लेख
भाषा:English
प्रकाशित: eLife Sciences Publications Ltd 2024-03-01
श्रृंखला:eLife
विषय:
ऑनलाइन पहुंच:https://elifesciences.org/articles/91826