Direct inference and control of genetic population structure from RNA sequencing data

Direct inference and control of genetic population structure from RNA sequencing data

Abstract RNAseq data can be used to infer genetic variants, yet its use for estimating genetic population structure remains underexplored. Here, we construct a freely available computational tool (RGStraP) to estimate RNAseq-based genetic principal components (RG-PCs) and assess whether RG-PCs can b...

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Bibliographic Details
Main Authors: Muhamad Fachrul, Abhilasha Karkey, Mila Shakya, Louise M. Judd, Taylor Harshegyi, Kar Seng Sim, Susan Tonks, Sabina Dongol, Rajendra Shrestha, Agus Salim, STRATAA study group, Stephen Baker, Andrew J. Pollard, Chiea Chuen Khor, Christiane Dolecek, Buddha Basnyat, Sarah J. Dunstan, Kathryn E. Holt, Michael Inouye
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05171-9

Internet

https://doi.org/10.1038/s42003-023-05171-9

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