Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity
<p>Abstract</p> <p>Background</p> <p>Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA), which mediate fibrinolysis. PAI-1 is also involved in the innate imm...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-06-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/9/1/149 |