Epigenetic regulation mechanism of folic acid deficiency inhibiting Brachyury expression and its effect on differentiation of embryoid bodies

Objective To investigate the epigenetic regulation mechanism of folic acid deficiency in inhibition of the expression of Brachyury, a key developmental gene, and its effect on the differentiation of embryoid bodies (EBs). Methods Firstly, the cell model of folic acid-deficient embryonic stem cells...

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Bibliographic Details
Main Authors: CHANG Shaoyan, GUO Jiuye, CHEN Yan
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2022-07-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202201119.htm