A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli

A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli

The TIR-containing protein C (TcpC) of uropathogenic Escherichia coli strains is a powerful virulence factor by impairing the signaling cascade of Toll-like receptors (TLRs). Several other bacterial pathogens like Salmonella, Yersinia, Staphylococcus aureus but also non-pathogens express similar pro...

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Bibliographic Details
Main Authors: Anna Waldhuber, Greg A. Snyder, Franziska Römmler, Christine Cirl, Tina Müller, Tsan Sam Xiao, Catharina Svanborg, Thomas Miethke
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Pathogens
Subjects:
bacterial pathogens
Toll-like receptors
TIR-containing proteins
TIR-domain structure
Online Access:http://www.mdpi.com/2076-0817/5/1/25

Internet

http://www.mdpi.com/2076-0817/5/1/25

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