Connections between Exoproteome Heterogeneity and Virulence in the Oral Pathogen Aggregatibacter actinomycetemcomitans

Connections between Exoproteome Heterogeneity and Virulence in the Oral Pathogen Aggregatibacter actinomycetemcomitans

ABSTRACT Aggregatibacter actinomycetemcomitans is a Gram-negative bacterial pathogen associated with severe periodontitis and nonoral diseases. Clinical isolates of A. actinomycetemcomitans display a rough (R) colony phenotype with strong adherent properties. Upon prolonged culturing, nonadherent st...

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Bibliographic Details
Main Authors: Yanyan Fu, Sandra Maaβ, Marines du Teil Espina, Anouk H. G. Wolters, Yanan Gong, Anne de Jong, Erwin Raangs, Girbe Buist, Johanna Westra, Dörte Becher, Jan Maarten van Dijl
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mSystems
Subjects:
Aggregatibacter actinomycetemcomitans
exoproteome
serotype
virulence
secreted proteins
virulence factors
Online Access:https://journals.asm.org/doi/10.1128/msystems.00254-22

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https://journals.asm.org/doi/10.1128/msystems.00254-22

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