Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling

Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling

Abstract Background Epidemiological emerging evidence shows that human exposure to some nanosized materials present in the environment would contribute to the onset and/or progression of Alzheimer’s disease (AD). The cellular and molecular mechanisms whereby nanoparticles would exert some adverse ef...

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Bibliographic Details
Main Authors: Luiz W. Ribeiro, Mathéa Pietri, Hector Ardila-Osorio, Anne Baudry, François Boudet-Devaud, Chloé Bizingre, Zaira E. Arellano-Anaya, Anne-Marie Haeberlé, Nicolas Gadot, Sonja Boland, Stéphanie Devineau, Yannick Bailly, Odile Kellermann, Anna Bencsik, Benoit Schneider
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Particle and Fibre Toxicology
Subjects:
Nanoparticles
PrPC receptor
Signaling
TNFα receptors
Aβ peptides
Neuroinflammation
Online Access:https://doi.org/10.1186/s12989-022-00490-x

Internet

https://doi.org/10.1186/s12989-022-00490-x

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