ROP16 of <i>Toxoplasma gondii</i> Inhibits Innate Immunity by Triggering cGAS-STING Pathway Inactivity through the Polyubiquitination of STING
cGAS-STING signaling is a major pathway in inducing type Ⅰ IFN, which plays a crucial role in the defense against <i>T. gondii</i> infection. In contrast, <i>T. gondii</i> develops multiple strategies to counteract the host defense, causing serious diseases in a wide range of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-07-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/12/14/1862 |