The whole transcriptome analysis and the circRNA-lncRNA network construction in arsenic trioxide-treated mice myocardium

The whole transcriptome analysis and the circRNA-lncRNA network construction in arsenic trioxide-treated mice myocardium

Background/Aims: Arsenic trioxide (ATO) is an effective anti-cancer drug. Nonetheless, it possesses cardiotoxic effects which limit its clinical application. The present study aims to elucidate the molecular basis of ATO-induced cardiotoxicity through using whole transcriptome analysis. Methods: The...

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Bibliographic Details
Main Authors: Yanan Jiang, Xiuyun Shen, Chaorun Dong, Fengnan Zhi, Yang Gao, Chunpeng Shi, Yuqiu Chao, Jincheng Xu, Desi Shang, Juan Xu, Baofeng Yang, Xia Li, Yunlong Bai
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Arsenic trioxide
Cardiotoxicity
RNA sequencing
Noncoding RNA
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222005728

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http://www.sciencedirect.com/science/article/pii/S0753332222005728

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