Major adverse cardiovascular events are associated with necroptosis during severe COVID-19

Major adverse cardiovascular events are associated with necroptosis during severe COVID-19

Abstract Background The mechanisms used by SARS-CoV-2 to induce major adverse cardiac events (MACE) are unknown. Thus, we aimed to determine if SARS-CoV-2 can induce necrotic cell death to promote MACE in patients with severe COVID-19. Methods This observational prospective cohort study includes exp...

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Bibliographic Details
Main Authors: Rosana Wiscovitch-Russo, Elsa D. Ibáñez-Prada, Cristian C. Serrano-Mayorga, Benjamin L. Sievers, Maeve A. Engelbride, Surya Padmanabhan, Gene S. Tan, Sanjay Vashee, Ingrid G. Bustos, Carlos Pachecho, Lina Mendez, Peter H. Dube, Harinder Singh, Luis Felipe Reyes, Norberto Gonzalez-Juarbe
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Critical Care
Subjects:
COVID-19
Necroptosis
Heart injury
Online Access:https://doi.org/10.1186/s13054-023-04423-8

Internet

https://doi.org/10.1186/s13054-023-04423-8

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