Synthesis and Evaluation of Antileishmanial and Cytotoxic Activity of Benzothiopyrane Derivatives

Synthesis and Evaluation of Antileishmanial and Cytotoxic Activity of Benzothiopyrane Derivatives

In continuation of our efforts to identify promising antileishmanial agents based on the chroman scaffold, we synthesized several substituted <i>2H</i>-thiochroman derivatives, including thiochromenes, thichromanones and hydrazones substituted in C-2 or C-3 with carbonyl or carboxyl grou...

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Bibliographic Details
Main Authors: Cristian Ortiz, Fernando Echeverri, Sara Robledo, Daniela Lanari, Massimo Curini, Wiston Quiñones, Esteban Vargas
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
<i>leishmania</i>
thiochromenes
benzothiopyrans
thiochroman-4-ones
synthesis
leishmaniasis
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/25/4/800

Internet

https://www.mdpi.com/1420-3049/25/4/800

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