Pharmacokinetics and Metabolomic Profiling of Metformin and <i>Andrographis paniculata</i>: A Protocol for a Crossover Randomised Controlled Trial

Pharmacokinetics and Metabolomic Profiling of Metformin and <i>Andrographis paniculata</i>: A Protocol for a Crossover Randomised Controlled Trial

This protocol aims to profile the pharmacokinetics of metformin and <i>Andrographis paniculata</i> (AP) and continue with untargeted pharmacometabolomics analysis on pre-dose and post-dose samples to characterise the metabolomics profiling associated with the human metabolic pathways. Th...

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Bibliographic Details
Main Authors: Khim Boon Tee, Luqman Ibrahim, Najihah Mohd Hashim, Mohd Zuwairi Saiman, Zaril Harza Zakaria, Hasniza Zaman Huri
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Clinical Medicine
Subjects:
pharmacokinetics
metabolomics
metformin
<i>Andrographis paniculata</i>
clinical trials
Online Access:https://www.mdpi.com/2077-0383/11/14/3931

Internet

https://www.mdpi.com/2077-0383/11/14/3931

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