Modulatory Effects of Alpha-Mangostin Mediated by SIRT1/3-FOXO3a Pathway in Oxidative Stress-Induced Neuronal Cells

Backgroundalpha-Mangostin, a polyphenolic xanthone, is primarily found in the pericarp of mangosteen throughout Southeast Asia and is considered as the “Queen of Fruit” in Thailand. Nonetheless, it is not clarified how alpha-mangostin protects neuronal cells against oxidative stress.ObjectiveIn this...

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Bibliographic Details
Main Authors: Waralee Ruankham, Wilasinee Suwanjang, Kamonrat Phopin, Napat Songtawee, Virapong Prachayasittikul, Supaluk Prachayasittikul
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.714463/full