Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.

Genetic variations in a PTEN/AKT/mTOR signaling axis may influence cellular functions including cell growth, proliferation and apoptosis, and then increase the individual's risk of cancer. Accordingly, we explore the association between single nucleotide polymorphisms (SNPs) of these genes and...

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Bibliographic Details
Main Authors: Jiawei Chen, Pengfei Shao, Qiang Cao, Pu Li, Jie Li, Hongzhou Cai, Jian Zhu, Meilin Wang, Zhengdong Zhang, Chao Qin, Changjun Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3399895?pdf=render