Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing data

Abstract Background Understanding the mapping precision of genome-wide association studies (GWAS), that is the physical distances between the top associated single-nucleotide polymorphisms (SNPs) and the causal variants, is essential to design fine-mapping experiments for complex traits and diseases...

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Bibliographic Details
Main Authors: Yang Wu, Zhili Zheng, Peter M. Visscher, Jian Yang
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-017-1216-0