Isolation and Characterization of Human Monoclonal Antibodies to Pneumococcal Capsular Polysaccharide 3

Isolation and Characterization of Human Monoclonal Antibodies to Pneumococcal Capsular Polysaccharide 3

ABSTRACT The current pneumococcal capsular polysaccharide (PPS) conjugate vaccine (PCV13) is less effective against Streptococcus pneumoniae serotype 3 (ST3), which remains a major cause of pneumococcal disease and mortality. Therefore, dissecting structure-function relationships of human ST3 pneumo...

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Bibliographic Details
Main Authors: Rachelle Babb, Christopher R. Doyle, Liise-anne Pirofski
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:Microbiology Spectrum
Subjects:
Streptococcus pneumoniae
agglutination
immunology
immunotherapy
monoclonal antibodies
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.01446-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.01446-21

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