Gold nanoparticle distribution in advanced in vitro and ex vivo human placental barrier models

Gold nanoparticle distribution in advanced in vitro and ex vivo human placental barrier models

Abstract Background Gold nanoparticles (AuNPs) are promising candidates to design the next generation NP-based drug formulations specifically treating maternal, fetal or placental complications with reduced side effects. Profound knowledge on AuNP distribution and effects at the human placental barr...

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Bibliographic Details
Main Authors: Leonie Aengenheister, Dörthe Dietrich, Amin Sadeghpour, Pius Manser, Liliane Diener, Adrian Wichser, Uwe Karst, Peter Wick, Tina Buerki-Thurnherr
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Nanobiotechnology
Subjects:
Gold nanoparticle
Placental uptake and translocation
Ex vivo placenta perfusion
Placental in vitro co-culture model
Nanoparticle agglomeration
Online Access:http://link.springer.com/article/10.1186/s12951-018-0406-6

Internet

http://link.springer.com/article/10.1186/s12951-018-0406-6

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