Implementation of Double Immune Checkpoint Blockade Increases Response Rate to Induction Chemotherapy in Head and Neck Cancer

Implementation of Double Immune Checkpoint Blockade Increases Response Rate to Induction Chemotherapy in Head and Neck Cancer

To determine whether a single dose of double immune checkpoint blockade (induction chemoimmunotherapy (ICIT)) adds benefit to induction single-cycle platinum doublet (induction chemotherapy (IC)) in locally advanced head and neck squamous cell carcinoma (HNSCC), patients treated with cisplatin 30 mg...

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Bibliographic Details
Main Authors: Sabine Semrau, Antoniu-Oreste Gostian, Maximilian Traxdorf, Markus Eckstein, Sandra Rutzner, Jens von der Grün, Thomas Illmer, Matthias Hautmann, Gunther Klautke, Simon Laban, Thomas Brunner, Bálint Tamaskovics, Benjamin Frey, Jian-Guo Zhou, Carol-Immanuel Geppert, Arndt Hartmann, Panagiotis Balermpas, Wilfried Budach, Udo Gaipl, Heinrich Iro, Rainer Fietkau, Markus Hecht
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
combined modality therapy
head and neck neoplasms
induction therapy
double immune checkpoint inhibition
immunotherapy
HPV-positive OPSCC
Online Access:https://www.mdpi.com/2072-6694/13/8/1959

Internet

https://www.mdpi.com/2072-6694/13/8/1959

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