Insights into the Molecular Mechanisms Mediating Extravasation in Brain Metastasis of Breast Cancer, Melanoma, and Lung Cancer

Brain metastasis is an incurable end-stage of systemic cancer associated with poor prognosis, and its incidence is increasing. Brain metastasis occurs through a multi-step cascade where cancer cells spread from the primary tumor site to the brain. The extravasation of tumor cells through the blood–b...

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Bibliographic Details
Main Authors: Rama Alsabbagh, Munazza Ahmed, Mohammad A. Y. Alqudah, Rifat Hamoudi, Rania Harati
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/8/2258