LINflow: a computational pipeline that combines an alignment-free with an alignment-based method to accelerate generation of similarity matrices for prokaryotic genomes
Background Computing genomic similarity between strains is a prerequisite for genome-based prokaryotic classification and identification. Genomic similarity was first computed as Average Nucleotide Identity (ANI) values based on the alignment of genomic fragments. Since this is computationally expen...
Main Authors: | Long Tian, Reza Mazloom, Lenwood S. Heath, Boris A. Vinatzer |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2021-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/10906.pdf |
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